An absence of indicators for sickle cell illness or trait on a blood check signifies a standard hemoglobin construction. This consequence is usually decided by inspecting the hemoglobin protein via strategies like electrophoresis or high-performance liquid chromatography (HPLC). As an example, a standard hemoglobin electrophoresis sample will primarily present Hemoglobin A, with doable small quantities of Hemoglobin A2 and Hemoglobin F.
Such an consequence provides beneficial info for people involved about their sickle cell standing, particularly for these with a household historical past of the illness or originating from populations the place the trait is prevalent. Traditionally, correct and accessible testing has been essential in decreasing the incidence of the illness via knowledgeable reproductive selections and early intervention. A standard consequence alleviates issues relating to potential well being problems related to sickle cell illness, equivalent to painful crises, organ injury, and anemia.